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Novel histone deacetylase inhibitor AR-42 exhibits antitumor activity in pancreatic cancer cells by affecting multiple biochemical pathways.

机译：新型组蛋白去乙酰化酶抑制剂aR-42通过影响多种生化途径在胰腺癌细胞中表现出抗肿瘤活性。

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Yi-Jin Chen; Wen-Hung Wang; Wan-Yu Wu; Chia-Chi Hsu; Ling-Rung Wei; Sheng-Fan Wang; Ya-Wen Hsu; Chih-Chuang Liaw; Wan-Chi Tsai;
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1. The novel histone deacetylase inhibitor, AR-42, inhibits gp130/Stat3 pathway and induces apoptosis and cell cycle arrest in multiple myeloma cells. [J] . Zhang S, Suvannasankha A, Crean CD, International Journal of Cancer =: Journal International du Cancer . 2011,第1期

机译：新型组蛋白脱乙酰基酶抑制剂AR-42抑制gp130 / Stat3途径并诱导多发性骨髓瘤细胞凋亡和细胞周期停滞。
2. Histone deacetylase inhibitor AR-42 enhances E7-specific CD8+ T cell-mediated antitumor immunity induced by therapeutic HPV DNA vaccination [J] . LeeS.Y., HuangZ., KangT.H., Journal of molecular medicine: Official organ of the "Gesellschaft Deutscher Naturforscher und Arzte." . 2013,第10期

机译：组蛋白脱乙酰基酶抑制剂AR-42增强治疗性HPV DNA疫苗诱导的E7特异性CD8 + T细胞介导的抗肿瘤免疫
3. Suppression of Tumor Growth and Muscle Wasting in a Transgenic Mouse Model of Pancreatic Cancer by the Novel Histone Deacetylase Inhibitor AR-42 [J] . Sally E. Henderson, Li-Yun Ding, Xiaokui Mo, Neoplasia: an international journal for oncology research . 2016,第12期

机译：新型组蛋白去乙酰化酶抑制剂AR-42抑制胰腺癌转基因小鼠模型中的肿瘤生长和肌肉萎缩。
4. The Tricyclic Antidepressant Amitriptyline Inhibits D-Cyclin Transactivation and Induces Myeloma Cell Apoptosis by Inhibiting Histone Deacetylases: In Vitro and In Silico Evidence [C] . Xinliang Mao, Depei Wu, Suzanne Trudel, International conference of molecular simulations and applied informatics technologies . 2012

机译：三环抗抑郁药阿米替林通过抑制组蛋白脱乙酰基酶抑制D-cyclin反式激活并诱导骨髓瘤细胞凋亡：体外和计算机证据。
5. Application of Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-induced Cachexia [D] . Tseng, Yu-Chou. 2017

机译：组蛋白脱乙酰基酶抑制剂AR-42在癌症引起的恶病质中的应用
6. Novel histone deacetylase inhibitor AR-42 exhibits antitumor activity in pancreatic cancer cells by affecting multiple biochemical pathways [O] . Yi-Jin Chen, Wen-Hung Wang, Wan-Yu Wu, -1

机译：新型组蛋白脱乙酰基酶抑制剂AR-42通过影响多种生化途径在胰腺癌细胞中表现出抗肿瘤活性
7. The novel histone deacetylase inhibitor, AR-42, inhibits gp130/Stat3 pathway and induces apoptosis and cell cycle arrest in multiple myeloma cells [O] . Zhang Shuhong, Suvannasankha Attaya, Crean Colin D., 2011

机译：新型组蛋白脱乙酰基酶抑制剂AR-42抑制gp130 / Stat3途径并诱导多发性骨髓瘤细胞凋亡和细胞周期停滞

Novel histone deacetylase inhibitor AR-42 exhibits antitumor activity in pancreatic cancer cells by affecting multiple biochemical pathways.

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